Nottingham Genomics Laboratory Service (NGLS)

The Nottingham Genomics Laboratory Service (NGLS) forms part of the integrated ‘East Genomic Laboratory’ (East GLH) service. NGLS is a UKAS accredited medical laboratory No. 8031. 

The East GLH is responsible for delivery of the genomic tests defined in the new National Genomic Test Directories.  The tests will be either delivered locally or via the East GLH laboratory hub at Addenbrooke’s Hospital, Cambridge. For current turnaround times please see table below.

By sending a sample, accompanied by a completed laboratory request form, the user enters into a service agreement for the Nottingham Genomics Laboratory Service (NGLS) to provide the service or test requested and agrees to the terms and conditions.

For further details of the tests delivered locally, select the links below to go to the pages for the Cytogenetics, Molecular Genetics and Molecular Diagnostics sections of the laboratory. 

Information about updates to genomic testing can be found on the East GLH website at East Genomics Updates. If you are interested in receiving regular updates about genomic testing in the East GLH you can sign up here — East Genomics Update Form.

The NGLS is currently operating with reduced staff, as such some testing may take longer than usual, although teams are working hard to continue meeting target NHS turnaround times for as many tests as possible. Please see Genomics letter to service users Jan 2026 for further details

East GLH and Nottingham University Hospitals NHS Trust comply with the Data Protection Act and the General Data Protection Regulation (GDPR) and take all possible care to maintain security and confidentiality of personal data.

When required by law or contractual obligation the laboratory will release confidential information. Any request to share patient information is managed and approved in accordance with NUH policies.  

Further information on how patient data is maintained can be found here:

Data Requests & Your Privacy | NUH

 

Page last updated 03/02/2026. Please note that if printed, this information is only valid on the day of printing

Current turnaround times

 

March 2026

Rare Disease Cytogenomics

 

 

 

Tests

NHSE Target TAT (Days)

Percentage within Standard

Average TAT (Mean days)

Microarray / karyotypes for prenatal / urgent postnatal (e.g. neonatal referrals)

14

73%

12.6

Standard paediatric or fetal loss microarray

42

70%

40.4

Postnatal karyotyping (e.g. fertility or familial microarray follow-up)

42

14%

56.1
       

Rare Disease Molecular

 

 

 

Tests

NHSE Target TAT (Days)

Percentage within Standard

Average TAT (Mean, Days)

QF-PCR for rapid trisomy detection

3

73%

2.6

Prenatal diagnosis

3

100%

2.5

Targeted tests where the result is needed urgently

14

93%

11.9

Predictive testing

14

85%

13.5

Rare disease single gene screening, known familial variant testing & standard STR based analysis

42

83%

40.3

Rare disease small panel testing (<10 genes)

42

60%

45.8

WGS

84

50%

85.5
       

Haem-Onc Cytogenomics

 

 

 

Tests

NHSE Target TAT (Days)

Percentage within Standard

Average TAT (Mean, Days)

PML::RARA FISH

3

100%

1

BCR::ABL1 (ALL) FISH

3

83%

2.5

CBF AML FISH

3

82%

2.6

Diagnostic CML, AML, ALL. Urgent lymphoma

7

39%

8

Follow-up haemato-oncology

14

83%

9.9

MDS, MPN, myeloma, remission samples.

21

35%

25.4
       

Haem-Onc Molecular

 

 

 

Tests

NHSE Target TAT (Days)

Percentage within Standard

Average TAT (Mean, days)

AML (FLT3, NPM1)

3

23%

4.3

AML NGS Panel

14 (7 local)

100%

6.4

MPN (JAK2, CALR)

21

43%

22.5

Chimerism

14

73%

13

Diagnostic BCR::ABL1

14

59%

14.2

Diagnostic BCR::ABL1 (exclusion)

21

83%

17.9

Monitoring BCR::ABL1

14

42%

14.8
       

Solid Cancer

 

 

 

Tests

NHSE Target TAT (Days)

Percentage within Standard

Average TAT (Mean, Days)

Urgent FISH for solid cancers*

7

100%

3

BRAF

7

100%

2.8

NGS-targeted DNA

14

95%

9.6

NGS-targeted RNA

14

96%

9.6

Routine FISH for solid cancers

14

87%

11.1

* February 2026 data