If you have symptoms of coronavirus (COVID-19) – a high temperature, a new continuous cough, or a loss of, or change in, your normal sense of smell or taste (anosmia) – the advice is to stay at home for 10 days. All members of this household should remain at home for 14 days.

If you think you have symptoms, please do not attend your hospital appointment until you are advised it is safe to do so. Please contact us to rearrange your appointment, or to re-organise treatment and tests.

The latest information on the Covid-19 vaccination programme in Nottingham and Nottinghamshire can be found here.

Live trials for COVID-19

COVID-19 trials

We are carrying out a number of trials for patients who are being treated at, or admitted to NUH for COVID-19.

Our research is part of the national and international response to COVID-19. Our expert clinical research teams are helping to find the most effective drugs, vaccines and treatments. Our aim is to offer every patient with suspected or confirmed COVID-19 the opportunity to take part in this vital research.

Taking part

If you are admitted or referred to NUH with suspected or confirmed COVID-19, your clinical team and our research nurses (who specialise in supporting patients taking part in clinical trials) will talk to you about taking part in COVID-19 research here.

Research trials into new COVID-19 vaccines are open to people who are healthy (and do not have COVID-19).

Take part in a trial

Take part in a trial

At NUH we run hundreds of clinical trials every year. We are only able to do this because our patients, carers and families volunteer to take part in and support our research.

Take part in a trial at NUH

Our aim is to offer every patient the opportunity to take part in clinical research at our hospitals. You can ask the team caring for you about research taking place now.

In 2019/20 over 14,000 people took part in clinical trials here, enabling us to test new treatments, technology and therapies which will help to improve healthcare for thousands of people.

COVID-19 research

Our planned programme of research has changed in the last year. In response to the pandemic, we prioritised research to support patients admitted to NUH with COVID-19. Your can find details on our COVID-19 trials page.

Long Covid research

Our COVID-19 research is also looking at the longer-term effects for patients who are recovering, but still expriencing symptoms which are impacting on their lives. You can find details on our Long Covid trials page.

Research into other diseases 

You can see some of the trials currently open and looking for people to take part on our Live Trials pages.

Please check with your Research Team about how COVID-19 may be impacting on research studies that you are taking part in.

Ask your clinical team about research

Please ask your clinical team about research trials that you may be able to take part in at NUH.

Who can take part in a clinical trial?

It depends on the trial. Some trials (usually Phase 2 or 3 trials) use only people with certain diseases or conditions, or whose family members have certain diseases or conditions. Other trials can use people who are healthy.

Not everyone who wants to be in a trial can be in one. To be in a trial, you need to meet certain conditions. Often, you need to have the disease or problem being studied. Other conditions usually have to do with the health of your heart, liver, kidneys, or other organs. To see if you meet the conditions needed for the research, you might need to answer questions or undergo a medical examination or tests like blood tests.

If you are a patient at NUH, you will usually be asked by the doctors or nurses treating you if you would be willing to take part in current research happening in our hospitals.  You are free to say yes or no, and your treatment and care will not be affected by what you decide.

Learn more about clinical trials

A clinical trial is a research study that uses people to find new ways to improve healthcare. Trials are vital to the development of the quality and effectiveness of the health and social care that patients receive. Clinical trials help to provide the answers to the health problems we have today and ensure that the next generation of patients will receive better care.  Creating this new knowledge relies on current patients and members of the public volunteering to take part.

Clinical trials can:

  • test new treatments to see if they help with certain diseases or conditions better than the current treatments
  • test treatments or lifestyle changes to see if they prevent or lower the chance of getting certain diseases
  • test new ways of finding out if people have certain diseases

 

Clinical trials that test new treatments, such as medicines, fall into one of three types. The type of trial depends on its goal and how much testing the treatment has already had.

The different types of treatment trials are:

  • phase 1 (I) trials – in Phase 1 trials, researchers check the safety of a new treatment. They learn how the medicine should be given, how often it should be given, what dose is safe, and what the side effects are.
  • phase 2 (II) trials – in Phase 2 trials, researchers give a new treatment to a group of people with a certain disease. They check the treatment's side effects and how well it works to treat the disease.
  • phase 3 (III) trials – in Phase 3 trials, researchers compare a new treatment with the current treatment for a certain disease. They learn if the new treatment helps the disease better, worse, or the same as the current treatment. They also learn if the new treatment has more or fewer side effects than the current treatment.

What are the benefits of taking part in a clinical trial?

People can benefit from taking part in clinical research trials in different ways:

  • Help to advance scientific and clinical knowledge about our health and wellbeing
     
  • the chance to test a new treatment at an early stage
  • work with research experts who have a great deal of knowledge of the disease and have your progress regularly monitored
     
  • help people who will have your disease in the future, by supporting the development of new and more effective treatments, therapies or medicines
     
  • learn about your health and about clinical research in general

Before deciding whether taking part in a clinical research trial is right for you, you should consider all of the information available to you from the research teams. They will explain how the trial will work, any risks or side-effects that you may experience and also the benefits of the treatments being tested. They will also explain any downsides to taking part, for example that the new treatment they are testing could be less effective than the treatment you are already receiving.

Please be aware that:

  • You might not get the new treatment – our research will compare a new treatment with the "usual" treatment for a disease. Other studies compare a new treatment with a "placebo". A placebo is a treatment that looks the same as medicine and is given the same way, but doesn't have any medicine in it. A placebo is used only if doctors aren't sure that the usual treatment helps or if there isn't any good treatment for that disease or condition.
     
  • In studies that compare two treatments, half of the people get the new treatment, and the other half get the usual treatment or placebo. Neither you nor your researchers can choose which treatment you get. Also, in many cases, you won't know which treatment you got until the trial is over.

If you decide to take part in a trial, you will need to give your written consent.

Consent

Make sure you're happy with the trial and have been given all the information you want before you give your consent (permission). This may mean taking some time to think about it and talk it over with family or friends, unless a decision is needed urgently because of your medical condition.

If you decide to take part, you'll be asked to sign a form to say you're agreeing to take part in a trial and have understood what it involves. This is called giving your informed consent. 

For people under the age of 18, a parent or guardian has to give informed consent.

Using your data in our research

Using your data

Protecting your information

Our research is only possible because of the patients, families and carers who agree to use their data as part of our research. At every stage of our research, we are committed to protecting your privacy, confidentiality and dignity. That includes using your data responsibly.

Our researchers are specially trained, qualified and authorised to work with your data. We handle and store data in the most secure ways possible. We will only use your data with the proper approvals, following independent review of how we plan to use the data for research and with full security of your data in place. We will only use your data to improve health and care.

The video above summarises how the NHS uses data to save lives and improve treatment and care; we are grateful to the Understanding Patient Data initiative for these resources. You will find more information and resources on the Understanding Patient Data website.

Our commitment to you

At NUH we make the following commitments about the data we keep about you and the way that we protect it. We will:

  • Keep the right information to provide services and fulfil our legal responsibilities to you
  • Keep your records safe, secure and accurate
  • Only keep your information as long as necessary
  • Collect, store and use the information you provide to the data protection standards and the laws that govern data protection
  • Comply with the NUH Privacy Policy and the General Data Protection Regulation (GDPR), which requires that the way we manage your personal data is fair, lawful and transparent.

Sharing data for research

By bringing together small amounts of data from many thousands of patients, health researchers and scientists can look for patterns across the population. This type of data analysis can be used to help:

  • understand more about disease risks and causes
  • improve diagnosis
  • develop new treatments and prevent disease
  • plan NHS services
  • improve patient safety

How the NHS uses data for research in the UK

The Health Research Authority (HRA) is the national body which protects and promotes the interests of patients and the public in health and social care research. It provides information about how data is used for research in the UK. You can find details of this information on the HRA website.

Choose how your data is used

You can choose if your health data is used for clinical research or for NHS and social care planning. Find out about how health data is used nationally and about your choices on the NHS website.

Data Opt Out

You can choose how your data is used by the NHS for planning and clinical research.

Find out more about the Data Opt Out on the NHS Digital website.

Our partners

We are working with our partners in the University of Nottingham to develop the skills and capabilities to analyse extremely large amounts of data for research.

We are also working nationally as part of information collaborations and new developments in research data to improve healthcare across the country.  

Your safety

Our experts check all trials – before and during them – to make sure that they are safe. Our research is also accredited by the relevant national regulatory or sponsoring organisation to ensure that we consistently meet all of the standards required to carry out clinical research in the UK. If there are signs that the treatment in a trial could be unsafe, the research team or the regulators will stop the trial. 

During the trial, you will need to follow all of the instructions about visits, tests, and treatments. This may be over a period of days, weeks or months. If you experience any problems, issues or side-effects, you should contact your research doctor or nurse.

You may decide to stop taking part in a trial if your condition is getting worse or if you feel the treatment isn't helping you. You can also choose to leave at any point without giving a reason and without it affecting the care you receive.