Sample requirements
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Investigation |
Sample requirements |
Result/report available |
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Lymphoid clonality Ig gene rearrangement TCR gene rearrangement |
Minimum of 3 FFPE embedded tissue scrolls or 1mL EDTA peripheral blood |
*Outsourced to Cambridge |
| Genexus OPA Panel |
Minimum of 50μm FFPE tissue sectioned at 10μm (5x10 μm):
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*Note we are currently outsourcing B and T cell clonality analysis to Cambridge, please forward all material to NUH laboratory for extraction (FFPE embedded tissue or EDTA peripheral blood).
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Investigation |
Sample requirements |
Result/report available |
|
Acute Myeloid Leukaemia (AML)- rapid analysis/fusion detection* |
Minimum of 3.5mL EDTA-anticoagulated peripheral blood/bone marrow |
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FLT-3 ITD/TKD |
Up to 3 working days |
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NPM1 |
Up to 3 working days |
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CBFβ-MYH11 inv(16) |
Up to 14 calendar days* |
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AML1-ETO t(8;21) |
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IDH1 and IDH2 mutation testing (Not included in Paediatric AML) |
Minimum of 1mL EDTA-anticoagulated peripheral blood/bone marrow |
Upto 14 calendar days* |
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APML-fusion detection PML-RARA t(15;17) |
Minimum of 3mL EDTA-anticoagulated peripheral blood/bone marrow |
Upto 3 working days |
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CML- fusion detection BCR::ABL t(9;22) |
Minimum of 3mL EDTA-anticoagulated peripheral blood/bone marrow |
Upto 7 calendar days |
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CML- MRD monitoring BCR::ABL t(9;22) p210 major transcripts (note we do not offer MRD testing for minor p190 transcript type) |
Minimum of 9mL EDTA-anticoagulated peripheral blood/bone marrow |
Upto 14 calendar days* |
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Myeloproliferative neoplasms JAK2, CALR |
Minimum of 1mL EDTA-anticoagulated peripheral blood/bone marrow |
Upto 14 calendar days |
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Post BMT Chimerism MRD |
Minimum of 1mL EDTA-anticoagulated peripheral blood/bone marrow |
Upto 14 calendar days |
*For clinical urgency based upon priority clinical needs, a request can be made and a 1 week turnaround time arranged with the Lab.
Note, it is not necessary to take separate blood tubes for each DNA request.
Page last updated 17/01/2024. Please note that if printed, information is only valid on the day of printing.